Thousands of old family photos. Boxes of keepsakes. A storage room I can barely turn around in. Then one thought stopped me cold: What if nobody even wants any of it?

I finally learned the game that had fascinated me for years—and promptly became obsessed. Mahjong has brought challenge, laughter, friendship and a whole lot of fun around the table.

Can Alzheimer’s actually be prevented? After watching the disease affect my mother—and learning that I carry APOE4—I wanted more than hopeful headlines. This article looks at what human research says may truly move the needle, from blood pressure, diabetes and exercise to sleep, hearing, nutrition, connection and the growing hope surrounding new trials and AI.